Usoro na aha kemịkalụ:
Aha INCI:Troxerutin/Troxerutin
Aha otutu:Vitamin P4, Trihydroxyethyl Rutin
CAS Mba:7085-55-4
Arọ molikula:742.7 g/mol
Usoro ihe omimi:C33H42019
Njirimara ngwaahịa
"Katalọgụ nke aha eji achọ mma Raw Materials(2015 Edition)" nke National Drug Administration weputara gụnyere troxerutin na katalọgụ a nwere nọmba 05450.
1 Ọrụ ndu na capillaries
Troxerutin nwere ike igbochi nchịkọta nke mkpụrụ ndụ ọbara uhie na platelet, na-abawanye nguzogide vaskụla nke obere akwara, na-egbochi mmụba nke capillary permeability ma belata ọbara ọgbụgba nke capillaries, na-egbochi thrombosis, na-eme ka microcirculation dịkwuo mma, na-abawanye ọdịnaya oxygen n'ime ọbara, na-akwalite ahụ ike. Nhazi nke arịa ọbara ọhụrụ iji meziwanye mgbasa nke ụdọ akụkụ, wdg. Ya mere, a na-ejikarị ya eme ihe na ụlọ ọgwụ na-agwọ ọrịa thrombosis nke ụbụrụ ụbụrụ, thrombophlebitis na ọbara ọgbụgba.
2 Na-amịkọrọ ultraviolet nke ọma ma guzogide ọkụ na-acha anụnụ anụnụ
UV irradiation nwere ike ime ka akpụkpọ ahụ mebie, mwepu akpụkpọ ahụ, na ịka nká, yana mmetụta nke ìhè na-acha anụnụ anụnụ (400nm ~ 500nm) na ìhè a na-ahụ anya na akpụkpọ ahụ enweghị ike ileghara anya. dermis, na-akpaghasị usoro nke circadian nke akpụkpọ ahụ, na-eme ka akpụkpọ ahụ dịkwuo elu ma na-eme ka akpụkpọ ahụ dị nro.
3 Iguzogide mmebi UV
(1) Ọ nwere ike igbochi apoptosis nke UVB nke mkpụrụ ndụ HaCaT (keratinocytes na-adịghị anwụ anwụ nke mmadụ), na-egbochi MAPK ngbanwe ụzọ ntụgharị na ihe ederede AP-1 (c-Fos na c-Jun), ma si otú ahụ na-ekere òkè n'iguzogide mmebi ọkụ;
(2) Enwere ike ịhazi okwu nke miRNA iji chebe nHDFs (fibroblasts) site na nrụgide oxidative na-akpata UV na mmebi DNA.
4 Antioxidant
Ọmụmụ ihe mbụ egosila na troxerutin nwere ike igbochi radieshon na-akpata lipid peroxidation na organelle subcellular, membranes cell na anụ ahụ nkịtị nke ụmụ oke etuto.
Troxerutin megide hydroxyl radical na ABTS.+Mmetụta mkpochapụ nke free radicals yiri nke VC, nke nwere ike jikọta ya na ìgwè phenolic hydroxyl na-arụ ọrụ na mgbanaka aromatic.
5 Kwalite ọrụ mgbochi akpụkpọ ahụ
Troxerutin nwere ike ịhazi miR-181a iji mee ka ọdịiche nke keratinocytes dịkwuo elu, mee ka usoro mgbidi brik" dị n'ahụ akpụkpọ ahụ, wee mee ka ọrụ mgbochi akpụkpọ ahụ dịkwuo elu. protein akpụkpọ anụ, na filaggrin) kwadoro na troxerutin nwere ike ịkwalite keratinocyte iche.
Ngwa ngwaahịa
Usoro akwadoro bụ 0.1-3.0%.
★ Anti-acha anụnụ anụnụ na ngwaahịa
★ Ngwaahịa na-ewepu ọbara uhie
★Mgbochi ịka nká ngwaahịa
★ ude ụkwụ
★ ngwaahịa mkpuchi anwụ
★ Ngwaahịa maka iwepu ọchịchịrị okirikiri n'okpuru anya
★ ngwaahịa ọcha
★ Mmezi ngwaahịa
Ngwa ngwa ngwa
Troxerutin dị mfe soluble na mmiri ma kwụsie ike na ọkụ na okpomọkụ; Enwere ike ịgbakwunye ya ozugbo usoro ahụ dị n'okpuru 45 ℃.
Nkọwapụta ngwaahịa
1kg / akpa, 25kg / gbọmgbọm
Nchekwa
Na-echekwa n'ebe dị jụụ, akọrọ na ọchịchịrị, nke a na-ekpuchi maka nchekwa, a ga-ejikwa ya ozugbo enwere ike imeghe ya. N'okpuru ọnọdụ nchekwa akwadoro, ngwaahịa ndị na-emegheghị nwere ndụ nchekwa nke ọnwa 24.
