API dị ọkụ ire ere CAS 700-06-1 Indole-3-Carbinol 99% ntụ ntụ

Ozi ngwaahịa

Aha:Indole-3-carbinol

Aha otutu:Indole-3-methane

Nọmba CAS:700-06-1

Usoro kemịkalụ:C9H9NO

Ọdịdị molekụla:

Nkọwapụta:99% HPLC

Agba:ọcha ntụ ntụ

Mmetụta nke Indole-3-carbinol

1. Anti-hormone-dị ka ọrụ: Indole-3-methanol nwere ike imetụta metabolic ụzọ nke estrogen, mụbaa ọrụ nke estradiol 2-hydroxylase na metabolic larịị nke catechol ụzọ, ma si otú na-abawanye larịị nke 2-hydroxy-estrone. homonụ.Ọ nwekwara ike ibelata mkpali nke glands nwanyị site na ibelata ụzọ 16a-hydroxy-estrogen, na-arụ ọrụ mgbochi homonụ na igbochi ụfọdụ etuto estrogen dabere.

2. Na-egbochi njikọ nke carcinogens na DNA: Indole-3-methanol nwere ike igbochi aflatoxin AFB1 ijikọta DNA, na-egbochi mmetụta na-eme ka AFB1 na-emepụta ihe na-emepụta ihe, ma na-egbochikwa njikọ nke DNA na-ejikọta na carcinogens na anwụrụ sịga.

3. Mezie metabolic enzyme ọrụ n'ime ahụ: Indole-3-methanol nwere ike ime ka ọrụ nke ọgwụ metabolizing enzymes na Phase I na Phase II, na-abawanye ọrụ nke glutathione na anụ ahụ na lekwasịrị akụkụ, transcriptionally na-akpali ọrụ nke glutathione S-transferase. (GST), epoxide hydrolase na quinone oxidoreductase NAD (P) H, na-ekere òkè na nbibi nke electrophiles.Na-echebe mkpụrụ ndụ pụọ na mmebi oxidative ma na-arụ ọrụ anticancer.

4. na mgbochi nke ọrịa cancer: oral indole-3-methanol nwere ike inye aka gbochie ọrịa cancer dị iche iche, gụnyere ọrịa ara ara, cancer uterine, prostate cancer na rectal cancer.

5. nkwado maka ọrụ imeju: indole-3-methanol nwere mmetụta nchebe ụfọdụ na imeju.

Ọrụ anyị

1.Ngwaahịa:Nye elu-edu, elu-ọcha osisi wepụ, ọgwụ akụrụngwa, na ọgwụ intermediates.

2.Ọrụ nka:Mwepụta ahaziri iche nwere nkọwa pụrụ iche dị ka ihe ndị ahịa chọrọ.