Ụlọ ọrụ GMP 7-epi-Paclitaxel CAS 105454-04-4 Standard

Ozi ngwaahịa

Aha:7-epi-Paclitaxel

Nọmba CAS:105454-04-4

Usoro kemịkalụ:C47H51NO14

Ọdịdị Molecular:

Nkọwapụta:karịa 99%

Agba:ọcha ntụ ntụ

Isi mmalite:Alaka na akwụkwọ osisi nke genus Taxaceae

Ụdị:Njikwa adịghị ọcha

Iji ngwaahịa

Ọ dabara maka R&D ọgwụ, mmepụta na nkwupụta.

Nkọwapụta ngwaahịa

Nkọwa:10mg/25mg/50mg/100mg na nkọwa ndị ọzọ bụ nhọrọ.

Hande mmepụta ike

Na ngwaahịa, nwere ike ahaziri dị ka ndị ahịa mkpa

Akwụkwọ ngwaahịa

Enyere ya ngwa ahịa:HPLC,NMR, MS spectrum na akwụkwọ COA.

Akụkọ ihe mere eme nke GMP

1.In 1996, e guzobere usoro mma na DMF nwetara.

2.In 2004,FDA nwetara CGMP akwụkwọ site na saịtị nyocha.

3.Na 2009, enwetara semi synthetic taxol DMF na eke taxol CEP.

4.Na 2011, enwetara semi synthetic taxol CEP.

5.In 2012, ọ gafere TGA na-saịtị nnyocha, nwetara GMP asambodo, na gafere FDA on-saịtị nnyocha.

6.2013, site na saịtị CGMP.

7.In 2015, India e debara aha na Japan e debanyere aha.

Ọrụ anyị

1.Ngwaahịa:Nye elu-edu, elu-ọcha osisi wepụ, ọgwụ akụrụngwa, na ọgwụ intermediates.

2.Ọrụ nka:Mwepụta ahaziri iche nwere nkọwa pụrụ iche dị ka ihe ndị ahịa chọrọ.