Kedu ihe kpatara paclitaxel na-ejikọta Albumin adịghị mkpa ka emechaa ya tupu ya emee?

Ka ọ dị ugbu a, e nwere ụdị nkwadebe paclitaxel atọ na ahịa na China, gụnyere paclitaxel injection, Liposomal paclitaxel na Albumin-bound paclitaxel. Ma paclitaxel injection na Liposomal paclitaxel maka injection kwesịrị ka a na-agwọ ya na ọgwụ pretreatment allergies, ma gịnị kpatara Albumin- bound paclitaxel adịghị mkpa ka a gwọọ ya? Ka anyị leba anya n'ihe ndị a.

Kedu ihe kpatara na paclitaxel na-ejikọta Albumin na-adịghị mkpa ka a gwọọ ya? Ugbu a, ka anyị ghọta usoro nrịanrịa nke nkwadebe paclitaxel atọ.

1.Paclitaxel ogwu ogbugba

Iji mee ka mmiri solubility nke paclitaxel dịkwuo elu, ihe mgbaze maka injection paclitaxel bụ mmanụ polyoxyethylene castor mmanụ na ethanol. Polyoxyethylene Castor mmanụ, dị ka allergen, nwere ụfọdụ ndị na-abụghị ionic ngọngọ copolymers na ya molekụla Ọdịdị, nke nwere ike na-akpali ahụ hapụ histamine. ma na-ebute mmeghachi ahụ nfụkasị ahụ. Tupu eji ụlọ ọgwụ eme ihe, a ghaghị iji glucocorticoids na antihistamines mee ihe maka ọgwụgwọ mbụ.

2.Liposomal paclitaxel

Liposomal paclitaxel bụ tumadi phospholipid bimolecular liposomes na dayameta nke 400 nm guzobere lecithin na cholesterol n'otu akụkụ. Ha enweghị polyoxyethylene castor mmanụ na zuru ezu ethanol nke nwere ike ịkpata allergies.

Otú ọ dị, nchọpụta ndị ọzọ egosila na paclitaxel n'onwe ya nwekwara ike ịkpata hypersensitivity, nke metụtara ịgbalite usoro ahụ ji alụso ọrịa ọgụ site na basophils, IgE na IgG. Ma e jiri ya tụnyere paclitaxel injection, mmeghachi omume nfụkasị ya dị ala. Ugbu a, Liposomal paclitaxel chọrọ ọgwụgwọ nrịanrịa tupu ejiri ya.

3.Albumin-bound paclitaxel

Albumin-bound paclitaxel, nke nwere albumin mmadụ dị ka onye na-ebu ya, nwere uru nke ire ere dị mfe na vivo, ịba ụba ọgwụ na etuto ahụ, ebumnuche siri ike na nrụpụta chemotherapy dị elu.

Na usoro nke I, II ma ọ bụ III ọmụmụ na albumin-bound paclitaxel, n'agbanyeghị na ọ dịghị pretreatment e mere, ọ dịghị oké hypersensitivity mmeghachi omume a hụrụ. Ya mere, a naghị atụ aro ọgwụgwọ tupu nchịkwa albumin bound paclitaxel ugbu a.

Mara: Enwere ike ịrụ ọrụ yana ngwa ewepụtara n'isiokwu a niile sitere na akwụkwọ ebipụtara.

Yunnan Hande Biotechnology Co., Ltd e ọkachamara na mmepụta nkepaclitaxel APIn'ihi na ihe karịrị 20 afọ, na bụ otu n'ime ụwa kwụụrụ onwe emepụta nke paclitaxel API, a osisi-enwetara mgbochi ọrịa cancer ọgwụ, nke US FDA kwadoro, European EDQM, Australian TGA, Chinese CFDA, India, Japan na ndị ọzọ mba regulatory ụlọ ọrụ. .Hande nwere ike inye ọ bụghị naanị dị elupaclitaxel akụrụngwa,ma ọ bụkwa ọrụ nkwalite teknụzụ metụtara usoro paclitaxel. Maka ozi ndị ọzọ, biko nweere onwe gị ịkpọtụrụ anyị na 18187887160.