Glabridin sitere na osisi Glycyrrhiza glabra, naanị dị na mgbọrọgwụ na azuokokoosisi nke Glycyrrhiza glabra (Eurasia), ọ bụkwa isi Isoflavone nke Glycyrrhiza glabra.Glabridinnwere whitening, antioxidant, mgbochi mkpali na mmetụta ndị ọzọ. N'ihi na dịtụ ala ọdịnaya nke glabridin na ike nke ịdị ọcha usoro, ọ nwere aha nke"na-acha ọcha gold".
1. Ụkpụrụ ọcha nke Glabridin
Tupu ịghọta ụkpụrụ ịcha ọcha nke glabridin, anyị kwesịrị ibu ụzọ ghọta nkenke ihe kpatara mmepụta melanin.
Njikọ nke melanin chọrọ ihe atọ bụ isi:
Tyrosine: Isi akụrụngwa maka imepụta melanin.
Tyrosinase: bụ isi ọnụego na-egbochi enzyme nke na-agbanwe tyrosine ka ọ bụrụ melanin.
Ụdị oxygen na-emeghachi omume: Tyrosine ga-ejikọta ya na oxygen na usoro nke ịmepụta melanin n'okpuru ọrụ nke Tyrosinase.
Tyrosinase nwere ike na-emepụta melanin mgbe niile. Ihe mkpali mpụga (gụnyere ụzarị ọkụ ultraviolet nkịtị, mbufụt, ihe nfụkasị ahụ, wdg) nwere ike iduga nzuzo nzuzo gabigara ókè, na-eduga na agba ojii.
N'otu oge ahụ, ụdị oxygen na-emeghachi omume (ROS) nke radieshon ultraviolet na-akpata nwere ike imebi akpụkpọ anụ phospholipid nke anụ ahụ, gosipụtara dị ka erythema na pigmentation na akpụkpọ ahụ. Ya mere, ROS bụ ihe nwere ike ime ka agba agba na akpụkpọ ahụ. ọgbọ ya nwere ike igbochi ọgbọ nke melanin na pigmentation.
2, The whitening uru nke Glabridin
Na nkenke, usoro nke ịcha ọcha na ntụpọ ntụpọ bụ usoro ịlụ ọgụ megide Tyrosinase na ụdị oxygen na-emeghachi omume.
Glabridin na-egbochi ọrụ Tyrosinase site na mmachi mmekọ nwoke na nwanyị, na-ewepụ akụkụ nke Tyrosinase na mgbanaka catalytic nke melanin, na-egbochi njikọta nke mkpụrụ na Tyrosinase, si otú a na-egbochi njikọ nke melanin.glabridinn'onwe ya nwere ezigbo antioxidant na mmetụta mgbochi mkpali.
Na mkpokọta,glabridintumadi na-egbochi melanogenesis site na ụzọ atọ: igbochi ọrụ Tyrosinase, na-egbochi ọgbọ nke ụdị oxygen na-emeghachi omume, na igbochi mbufụt.
Nnwale egosiwo na ọ bụ ngwa ngwa, ịrụ ọrụ nke ọma, na-acha akwụkwọ ndụ akwụkwọ ndụ na freckle na-ewepụ ihe mgbakwunye ịchọ mma. Enwere data nnwale na-egosi na mmetụta nke Glabridin na-acha ọcha bụ ugboro 232 karịa vitamin C nkịtị, ugboro 16 dị elu karịa hydroquinone (quinone), na 1164 ugboro karịa nke "arbutin".
Nkọwa: Enwere ike ịrụ ọrụ na ngwa ndị a kpọtụrụ aha n'isiokwu a niile sitere na akwụkwọ ọha nwere.
Oge nzipu: Jun-28-2023