Paclitaxel, dị ka ọgwụ mbụ chemotherapy ewepụtara na osisi eke, ka bụ otu n'ime ọgwụ ndị a na-ahụkarị na kemoterapi tumor ruo taa.Paclitaxelbụ ọgwụ mgbochi tumor sitere na osisi taxus, usoro ya na-eme bụ ịkwalite mkpokọta microtubule iji gbochie tumor cell mitosis.Ọ bụ otu n'ime ọgwụ mgbochi tumor kacha mma na ahịa ọgwụ, yana enwere nnukwu ihe achọrọ. na mba ụwa ahịa ọgwụ.Paclitaxel kewara n'ime eke paclitaxel na semi synthetic paclitaxel.Ka anyị leba anya na ọrụ nke 10-Dab Semi-Synthetic Paclitaxel na-esonụ ederede.
10-Dab Semi-Synthetic Paclitaxelbụ ihe na-emepụta paclitaxel semi synthetic nke nwere ihe omume ọgwụ dị ka paclitaxel eke.Paclitaxe bụ ọgwụ mgbochi ọrịa cancer dị irè, nke a pụrụ iji na-agwọ ụdị ọrịa cancer dị iche iche, dị ka ọrịa ara ara, ọrịa cancer ovarian, ọrịa cancer akpa ume na ọrịa eriri afọ. nke precursor 10-DAB nke paclitaxel site na semi synthetic ụzọ nwere ike ime ka mkpụrụ na ịdị ọcha nke paclitaxel, belata mmepụta ihe, na-eme ka paclitaxel na-adigide na akụ na ụba. Na mgbakwunye, 10-DAB n'onwe ya nwekwara ụfọdụ ọgwụ omume, dị ka ya inhibitory mmetụta. na ụfọdụ mkpụrụ ndụ tumo.
10-Dab Semi-Synthetic Paclitaxelnwere ike ịrụ ọtụtụ ọrụ na mmetụta, ọ bụghị naanị dị ka ihe etiti ngwaahịa maka ọgwụ, kamakwa dị ka akụrụngwa akụrụngwa maka ọgwụ.Site na ọdịdị, ọ na-egosi dị ka a na-acha ọcha crystal.Ọ bụ ihe a na-ejikarị eme ihe na ụlọ ọrụ ọgwụ ma nwee ike ịbụ. eji dị ka akụrụngwa maka ọgwụ, nke na-enwe mmetụta dị mma n'ịmepụta ọgwụ mgbochi nje dị iche iche.
Oge nzipu: Jun-01-2023