Paclitaxel bụ ọgwụ mgbochi ọrịa kansa nke a na-eji agwọ ọtụtụ ụdị ọrịa kansa. E sitere na ogbugbo osisi yew Pacific (Taxus pacifica) wee mepụta ya site na usoro sịntetik.Paclitaxelbụ nke otu ọgwụ a na-akpọ microtubule stabilizers.
Usoro mgbochi ọrịa cancer nkepaclitaxelgụnyere ọtụtụ akụkụ, ọkachasị gụnyere ndị a:
1.Mmụba microtubule kwụsie ike:Paclitaxel na-egbochi nkwụsi ike nkịtị nke microtubules site na ijikọ tubulin, nke bụ akụkụ nke cytoskeleton. Akụkụ bụ isi nke ọrịa cancer, yabụ na-egbochi nkewa sel site n'ịkwụsị microtubules bụ isi ihe na-egbochi ọrịa kansa nke paclitaxel.
2.Cell okirikiri njide:Paclitaxel nwekwara ike ime ka cell okirikiri njide, nke na-eme ka cancer mkpụrụ ndụ kwụsị na a kpọmkwem cell okirikiri oge, na-emekarị mitosis.
3.Na-akwalite apoptosis:Paclitaxel nwere ike igbochi mmepe nke ọrịa kansa site n'ịkpalite mkpụrụ ndụ kansa mebiri emebi ma ọ bụ nke na-adịghị mma ịbanye apoptosis (ọnwụ cell emepụtara) Nke a bụ usoro ọnwụ cell nke na-enyere aka wepụ mkpụrụ ndụ ndị na-adịghị mma.
4.Anti-angiogenesis:Paclitaxelnwekwara ike igbochi nhazi arịa ọbara ọhụrụ na gburugburu mkpụrụ ndụ kansa, nke dị mkpa maka uto tumor na ịgbasa.
N'ozuzu, paclitaxel bụ ọgwụ na-egbochi uto na nkewa nke mkpụrụ ndụ kansa, na-arụ ọrụ na mkpụrụ ndụ kansa site na usoro dị iche iche, ya mere a na-eji ya n'ọtụtụ ụdị ọgwụgwọ ọrịa cancer.
Cheta na: Uru nwere ike na ngwa ewepụtara n'isiokwu a sitere na akwụkwọ ndị e bipụtara.
Yunnan Hande Biotechnology Co., Ltd e lekwasịrị anya na mmepụta nkepaclitaxelmaka afọ 26, ma bụrụ onye na-emepụta onwe ya nke ọgwụ paclitaxel API nke United States kwadoro, European EDQM, Australia TGA, China CFDA, India, Japan na ụlọ ọrụ nchịkwa mba ndị ọzọ. Yunnan Hande paclitaxel, ọkọnọ ntụpọ. ,ụlọ ọrụ ozugbo ahịa,nabata ịjụ ase,18187887160(WhatsApp otu nọmba)
Oge nzipu: Ọktoba 11-2023