Natural Paclitaxel VS Semi-synthetic Paclitaxel (I)

Ọgwụ ngwaọrụ

Paclitaxel, dị ka ọgwụ mgbochi ọrịa kansa, na-ejikarị n'ụdị injections na ngwaọrụ dị iche iche.

A na-eme ya nke ọma site na mmịpụta eke na njikọ.

Dị ka ihe ọkụkụ nke paclitaxel a na-amịpụta sitere n'okike, Taxus Chinensis, dị ụkọ ma nwee ogologo oge uto, usoro nhazi usoro ejirila nwayọọ nwayọọ nweta site na paclitaxel site na nyocha na nyocha gburugburu ụwa, gụnyere nchịkọta mkpokọta, ọkara njikọ, na njikọ endophytic.

N'ihi ogologo usoro njikọ nke kemịkalụ, ọtụtụ usoro njikọ, na-esikwa ike ịchịkwa ọnọdụ mmeghachi omume, paclitaxel synthesized n'ụzọ zuru ezu kwesịrị iji kemịkalụ kemịkalụ dị ọnụ karịa, mkpụrụ ahụ dịkwa ala, nke na-adabaghị maka mmepụta oke na mmepụta mmepụta ihe na izugbe.

Ya mere, a na-emepụta paclitaxel dịtụ ukwuu n'ahịa site na mmịpụta ebumpụta ụwa nke taxus azụlitere na ụzọ mkpụrụ sịntetik.

Natural Paclitaxel vs Semi-synthetic Paclitaxel

Akụkụ 1: Usoro mmepụta

Paclitaxel eke:

-Raw material:Eji aka kụrụ Yew

- Usoro mmịpụta: ihe ọkụkụ + chromatography kọlụm + recrystallization = ngwaahịa emechara

- Usoro mmịpụta: mmeghachi omume anụ ahụ, enweghị usoro njikọ kemịkalụ

Paclitaxel Semi-synthetic:

-Raw material:Eji aka kụrụ Yew

Usoro mmịpụta: ihe dị ndụ + kemịkalụ reagent mmeghachi omume + gbanyere kristal + mmeghachi omume kemịkal dị iche iche + recrystallization = ngwaahịa emechara

-Mmepụta usoro: chemical mmeghachi omume

N'ihe banyere nkà na ụzụ, paclitaxel eke nwere usoro mmịpụta dị mfe ma e jiri ya tụnyere paclitaxel semi-synthetic na uru ndị ọzọ karịa paclitaxel semi-synthetic n'ihe banyere nkwụsi ike na nchekwa, ebe paclitaxel semi-synthetic na-ebelata ọnụ ahịa mmepe ngwaahịa n'ihe gbasara ọnụ ahịa na akụrụngwa. ,ma na-emekwa ka nsogbu ụfọdụ kpatara ụkọ akụrụngwa n'ahịa.

E jiri ya tụnyere ụzọ abụọ nke imepụta paclitaxel, paclitaxel eke nwere nkwụsi ike na nchekwa dị mma na ngwaọrụ ahụike, nke bụ otu ihe mere ọtụtụ ụlọ ọrụ ngwaọrụ ahụike na ahịa na-eji paclitaxel eke eme ihe dị ka akụrụngwa.

Yunnan Hande Biotechnology Co., Ltd anọwo na-arụ ọrụ na mmepụta na mmepe nke taxes maka afọ 30, na ngwaahịa ya bụ paclitaxel eke, 10-DAB semi-synthetic paclitaxel, 10-deacetylbaccatin III, docetaxel, cabazitaxel, wdg. ozi ndị ọzọ gbasara paclitaxel APIs,biko kpọtụrụ anyị!!!(Whatsapp/Wechat:+86 18187887160)