Njirimara nke paclitaxel na-ejikọta albumin, ọgwụ mgbochi ọrịa kansa

Paclitaxel bụ ihe okike sitere na Taxus, nke na-arụ ọrụ na tubulin iji gbochie mitosis nke mkpụrụ ndụ tumo. ezigbo ụlọ ọgwụ dị irè na ọgwụgwọ nke ọrịa ara ara, ọrịa cancer ovarian, ọrịa cancer akpa ume na-abụghị obere cell, cancer gastroesophageal na etuto ndị ọzọ.

N'ihi na paclitaxel omenala bụ nke ukwuu lipophilic, na ihe na-arụsi ọrụ ike na-esiri ike igbari na mmiri, ethanol anhydrous, polyoxyethylene castor oil, etc. na-eji na nkwadebe usoro iji nyere ya aka igbari. Ndị a organic solvents dị mfe ime ka ihe nfụkasị ahụ na ndị ọrịa. na n'ọnọdụ ndị siri ike, ujo anaphylactic nwere ike ime, na-etinye ndụ n'ihe ize ndụ. Mmetụta nke mmeghachi ahụ nfụkasị ahụ dị elu dị ka 20% -40% maka mgbochi dị irè, a ghaghị ime ọgwụgwọ na corticosteroids na antihistamines tupu nchịkwa. Paclitaxel kwesịrị ka a gwakọta ya. nnukwu ọnụọgụ tupu ịgba ọgwụ mgbochi afọ, yana oge infusion kwesịrị ka edobe opekata mpe awa 3.

Iji merie ntụpọ a, albumin-bound paclitaxel bịara bụrụ. Albumin-bound paclitaxel na-ejikọta hydrophobic paclitaxel na albumin wee mepụta nanoparticles nwere urughuru ihe dịka 130 nm site na iji nanotechnology pụrụ iche. albumin na-eme ka paclitaxel kesaa karịa n'ime anụ ahụ tumo ma rute mkpokọta dị elu na sel tumor; Ọ na-ezere iji ethanol anhydrous, mmanụ polyoxyethylene castor mmanụ na ihe ndị ọzọ na-agbaze, na-ebelata nke ukwuu mmeghachi omume nfụkasị ahụ, ọ dịghịkwa achọ pretreatment antiallergic tupu eji ya. , ọ dịghịkwa mkpa iji ngwaọrụ infusion pụrụ iche. Enwere ike ịmecha infusion na ọkara otu awa. Ọ na-enweta mmetụta dị elu na-agwọ ọrịa na obere nsị.

Mara: Enwere ike ịrụ ọrụ yana ngwa ewepụtara n'isiokwu a niile sitere na akwụkwọ ebipụtara.

Yunnan Hande Biotechnology Co., Ltd e ọkachamara na mmepụta nkepaclitaxel APIn'ihi na ihe karịrị 20 afọ, na bụ otu n'ime ụwa kwụụrụ onwe emepụta nke paclitaxel API, a osisi-enwetara mgbochi ọrịa cancer ọgwụ, nke US FDA kwadoro, European EDQM, Australian TGA, Chinese CFDA, India, Japan na ndị ọzọ mba regulatory ụlọ ọrụ. .Hande nwere ike inye ọ bụghị naanị dị elupaclitaxel akụrụngwa,ma ọ bụkwa ọrụ nkwalite teknụzụ metụtara usoro paclitaxel. Maka ozi ndị ọzọ, biko nweere onwe gị ịkpọtụrụ anyị na 18187887160.