Paclitaxel, ihe sitere n'okike sitere na osisi Yew, abụrụla ihe na-agbanwe egwuregwu na ọgwụgwọ ọrịa cancer ruo ọtụtụ iri afọ. Otú ọ dị, njedebe dị oke na ọnụ ahịa dị elu nke iwepụta paclitaxel n'osisi yew emeela ka ndị ọkà mmụta sayensị mepụta ụzọ ọzọ. Ọbịbịa nke 10- deacetylbaccatin III (10-DAB) Semi-synthetic paclitaxel API, ntụ ntụ na-acha ọcha nke sitere na isi mmalite ihe ọkụkụ na-emegharị ọhụrụ, emeghewo ohere ọhụrụ na ngalaba nke oncology. Isiokwu a na-enyocha ike nke API semi-synthetic API na mmetụta ya na ọrịa cancer. ọgwụgwọ.
Nnweta na nkwado abawanyela:
Njikọ nke paclitaxel si10-DABna-enye ihe ngwọta na-adịgide adịgide na njedebe nke mmịpụta osisi yew. Ụzọ omenala na-egbute paclitaxel site na ogbugbo yew, na-akpata nchegbu gburugburu ebe obibi na mmachibido iwu. na nkwado nke ọgwụ a dị mkpa na-adịgide adịgide. Ọganihu a abụghị naanị na-eleba anya na gburugburu ebe obibi kamakwa ọ na-eme ka e nwee paclitaxel maka ndị ọrịa n'ụwa nile.
Ọnụ ahịa-arụmọrụ emelitere:
Mmepe nke10-DAB ọkara synthetic paclitaxel APInwere ikike ibelata ọnụ ahịa ọgwụgwọ ọrịa cancer nke ukwuu. Mmụba na ọnụ ahịa nke usoro mmepụta ihe na-enye aka na ọgwụ ndị dị ọnụ ala na ịnweta, na-ebelata ibu ego na ndị ọrịa na usoro nlekọta ahụike. Nke a na-emepe ọnụ ụzọ maka ohere ndị ọrịa ka ukwuu. ọgwụgwọ ndị na-azọpụta ndụ, na-emeziwanye nsonaazụ yana ọnụego nlanarị.
Ngwa ọgwụgwọ gbasaara:
E wezụga ọrụ ya guzosiri ike n'ịgwọ ọrịa ara, ovarian na akpa ume,10-DAB ọkara synthetic paclitaxel APIna-enye ohere na-akpali akpali maka ịgagharị ngwa ọgwụgwọ ọhụrụ. Ndị nchọpụta nwere ike nyochaa ịdị irè ya na ụdị ọrịa cancer dị iche iche, nwere ike gbasaa ojiji ya na ọrịa ọjọọ ndị a na-apụghị ịgwọta na mbụ. Ọzọkwa, nchikota 10-DAB paclitaxel na ndị ọzọ na-egbochi ọrịa cancer nwere ike ịmepụta mmetụta synergistic, na-akwalite ọgwụgwọ. nsonaazụ na ibelata nguzogide ọgwụ.
Ọgwụ ahaziri onwe ya na Oncology nke ọma:
Site na ịnweta 10-DAB semi-synthetic paclitaxel API, ọgwụ ahaziri onwe ya na nkenke oncology nwere ike ịga n'ihu. ibelata mmetụta dị n'akụkụ.Ngbanwe nke 10-DAB paclitaxel API na-enye ohere maka usoro ọgwụgwọ ahaziri ahazi, na-enye ndị ụlọ ọgwụ ike inye usoro ọgwụgwọ ezubere iche na nke ziri ezi.
Mmechi:
Okwu mmeghe nke10-DAB ọkara synthetic paclitaxel APIna-egosi akara ngosi dị ịrịba ama na ngalaba ọgwụgwọ ọrịa cancer. Nke a na-acha ọcha ntụ ntụ na-enye nkwalite nnweta, nkwado, na ọnụ ahịa ọnụ ahịa, na-agbanwe ohere nke paclitaxel. Site na ngwa ọgwụgwọ ya gbasaa na ikike nke ọgwụ ahaziri ahazi, 10-DAB paclitaxel API na-ekwe nkwa dị ukwuu. N'ịgbanwe ọdịdị ala nke nlekọta ọrịa cancer. Ka nyocha na mmepe na mpaghara a na-aga n'ihu, ọdịnihu nke ọgwụgwọ ọrịa cancer na-egbukepụ egbukepụ site na uru ndị nwere ike ịnweta nke ọhụrụ a dị ịrịba ama.
Oge nzipu: Mee-17-2023