Semi-synthetic paclitaxel bụ ọgwụ anticancer nke a na-ejikarị eme ihe na ụlọ ọgwụ, nke a na-ejikarị agwọ ọrịa cancer dị iche iche n'ihi nrụpụta ya dị ịrịba ama yana mmetụta dị ntakịrị na-egbu egbu. edinam na clinical ngwa nkeọkara sịntetik paclitaxeln'ụzọ zuru ezu.
Usoro nke ime ihe
Usoro nke ime iheọkara sịntetik paclitaxelbụ tumadi site n'igbochi polymerization nke tubulin, na-ebibi cell microtubule netwọk, si otú ahụ na-egbochi cell proliferation na ịkpalite cell apoptosis. Na mgbakwunye, semi-synthetic paclitaxel nwekwara ike ịhazi nzaghachi dịghịzi nke mkpụrụ ndụ tumo ma welie mgbochi tumor ike nke ahụ. .
Mmetụta ọgwụ
Semi-synthetic paclitaxel egosila ọrụ anticancer dị ịrịba ama na nyocha ọgwụ, ma nwee mmetụta ọgwụgwọ dị mma na ọrịa cancer dị iche iche dị ka ọrịa ara ara, ọrịa cancer akpa ume na ọrịa cancer akpa ume.
Mgbochi nke cell proliferation: semi-synthetic paclitaxel nwere ike igbochi mgbasa nke mkpụrụ ndụ tumo, karịsịa maka mkpụrụ ndụ na mitotic ogbo.
Ntinye nke apoptosis: paclitaxel semi-synthetic nwere ike ime ka apoptosis nke mkpụrụ ndụ tumo site na ịhazi usoro apoptosis nke mkpụrụ ndụ tumo, iji nweta ebumnuche ọgwụgwọ tumor.
Kwalite nzaghachi mgbochi ọrịa: paclitaxel semi-synthetic nwere ike ịhazi nzaghachi mgbochi nke mkpụrụ ndụ etuto ma welie ikike mgbochi tumor nke ahụ.
Ngwa ụlọ ọgwụ
A na-eji paclitaxel Semi-synthetic eme ihe n'ọtụtụ ebe n'ịgwọ ọrịa kansa dị iche iche, dị ka ọrịa ara ara, ọrịa ovarian, kansa akpa ume na ihe ndị ọzọ. Ọrịa cancer dị iche iche. N'iji ụlọ ọgwụ eme ihe, a na-ejikarị paclitaxel semi-synthetic na-ejikọta ya na ndị ọzọ na-ahụ maka chemotherapeutic iji meziwanye ọgwụgwọ ọgwụgwọ.
Mmetụta ndị na-egbu egbu
Mmetụta na-egbu egbu nke paclitaxel semi-synthetic dị ntakịrị, ma ọ ka nwere ike ịkpata mmeghachi omume ọjọọ, dị ka anaphylaxis, mbelata ụmị ọkpụkpụ, nsị obi, wdg. Na ngwa ụlọ ọgwụ, dọkịta ga-edozi usoro onunu ogwu na ugboro ole nke ọgwụ ahụ. dị ka ọnọdụ kpọmkwem nke onye ọrịa na ndidi nke ọgwụ ahụ iji belata mmetụta nke mmetụta ndị na-egbu egbu na onye ọrịa.
Atụmanya mmepe n'ọdịnihu
Site na ọganihu sayensị na nkà na ụzụ na-aga n'ihu na nyocha miri emi nke nyocha na paclitaxel, nchọpụta n'ọdịnihu na paclitaxel semi-synthetic ga-aba ụba na omimi.Na mgbakwunye na ịga n'ihu na-enyocha usoro nke ihe mgbochi ọrịa cancer ya, n'ihu. A ga-eme nyocha maka otu esi emeziwanye ọgwụgwọ ọgwụgwọ nke paclitaxel semi-synthetic ma belata mmetụta ya na-egbu egbu. ga-ekwe omume, na-enye ndị ọrịa cancer nhọrọ ọgwụgwọ ziri ezi ma dị irè karị.
Mmechi
Dị ka ọgwụ anticancer dị mkpa.ọkara sịntetik paclitaxelnwere ọtụtụ ngwa ụlọ ọgwụ. Mmetụta ọgwụgwọ ya dị ịrịba ama na mmetụta dị ntakịrị na-egbu egbu na-eme ka ọ bụrụ otu n'ime nhọrọ dị mkpa maka ọgwụgwọ ọtụtụ ọrịa cancer. N'ọdịnihu, nchọpụta na paclitaxel semi-synthetic ga-adị omimi karị na zuru oke, na-enye ụzọ ọgwụgwọ ka mma na olileanya nlanarị maka ndị ọrịa cancer.
Cheta na: Uru nwere ike na ngwa ewepụtara n'isiokwu a sitere na akwụkwọ ndị e bipụtara.
Oge nzipu: Nov-28-2023