Paclitaxel, a eke compound na ike mgbochi ọrịa cancer, aghọwo akụkụ dị mkpa nke cancer treatment.The umi, akpọ taxol, na-ewepụtara si ogbugbo nke yew osisi na bụ diterpenoid alkaloid.Over gara aga ole na ole iri afọ,paclitaxelegosila ọrịre dị ukwuu n'ịgwọ ọrịa kansa dị iche iche, gụnyere ara, ovarian, na ụfọdụ isi na olu na ọrịa cancer akpa ume.
Nke mbụ, ọrụ mgbochi ọrịa cancer nke paclitaxel bụ isi ihe na-emepụta ọgwụ, ọ nwere ike ịchịkwa uto mkpụrụ ndụ tumo ma gbochie mgbasa na metastasis nke etuto ahụ site na igbochi usoro unhelix nke DNA ma si otú ahụ gbochie DNA replication. A na-enweta nke ọma site n'ịkwụsị tubulin, igbochi mitosis na ịkpata apoptosis.
N'ime usoro ọgwụgwọ, a na-eji paclitaxel eme ihe n'ọtụtụ ebe n'ịgwọ ọrịa cancer ara. Na mgbakwunye, paclitaxel nwere ike ime ka ndụ ndị ọrịa dịkwuo mma, belata nlọghachi nke tumor, ma mee ka ndụ ndị ọrịa dịkwuo mma. Site n'igbochi DNA mmụgharị nke mkpụrụ ndụ tumo na ịkpata apoptosis, paclitaxel nwere ike ịchịkwa uto etuto nke ọma ma mee ka ogologo ndụ nke ndị ọrịa dị ogologo.
Na mgbakwunye na ọrịa kansa ara na ovarian.paclitaxelegosiwokwa ihe dị mma na ọgwụgwọ ụfọdụ ọrịa cancer isi na olu na ọrịa cancer akpa ume. N'ime ọgwụgwọ tumor ndị a, a na-ejikarị paclitaxel na-ejikọta ya na ọgwụ ndị ọzọ na-egbochi ọrịa cancer iji nweta mmetụta ọgwụgwọ dị irè karị.
Otú ọ dị, ọ bụ ezie na mmetụta ọgwụgwọ nke paclitaxel dị ịrịba ama, enwere ike inwe ụfọdụ mmeghachi omume ọjọọ n'oge a na-eji ya eme ihe. Mgbe ị na-eji paclitaxel, ọ dị mkpa iji nlezianya lelee ọnọdụ mmeghachi omume nke ndị ọrịa, yana ntinye aka n'ụlọ ọgwụ n'oge iji belata mmeghachi omume ọjọọ.
N'izugbe,paclitaxelekerewo òkè dị mkpa na ọgwụgwọ ọrịa cancer ma nwee mmetụta dị ịrịba ama megide ụdị ụbụrụ dị iche iche na-adịghị mma. Ọ bụ ezie na e nwere ụfọdụ mmeghachi omume ọjọọ, site na ntụziaka ọgwụ ezi uche dị na ya na nlekota nlekọta ahụike, ọ nwere ike belata ihe ize ndụ ya n'ụzọ dị irè ma mee ka mmetụta ọgwụgwọ ya dịkwuo elu.With na-aga n'ihu na-aga n'ihu. ọganihu nke sayensị na nkà na ụzụ na nghọta miri emi nke mmetụta ọgwụ nke paclitaxel site n'aka ndị nchọpụta, anyị nwere ihe mere anyị ga-eji kwenye na a ga-enwekwu ọgwụ paclitaxel ọhụrụ ma dị irè n'ọdịnihu, na-eweta ọtụtụ nhọrọ ọgwụgwọ na olileanya nye ndị ọrịa cancer.
Cheta na: Uru nwere ike na ngwa ewepụtara n'isiokwu a sitere na akwụkwọ ndị e bipụtara.
Oge nzipu: Nov-14-2023