Kedu ka esi eme paclitaxel Semi-synthetic?

Paclitaxel, a eke anti-cancer ọgwụ, bụ tumadi amịpụtara si Taxus chinensis.It e ọtụtụ-eji na ọgwụgwọ nke ara ara, ovarian cancer, na ụfọdụ isi na olu cancer na akpa ume cancer clinically.Paclitaxel na-ekewa n'ime eke.paclitaxelnaSemi-synthetic paclitaxelN'okpuru ebe a, ka anyị leba anya ka esi eme paclitaxel Semi-synthetic.

Ebe ọ bụ na a na-ewepụta paclitaxel eke sitere na Taxus chinensis na isi mmalite ole na ole, na usoro uto nke eke Taxus chinensis dị ogologo, naanị ihe dịka 13.6kg ogbugbo nwere ike wepụ 1g nke paclitaxel, ọ na-ewe 3 ruo 12 osisi taxus nwere akụkọ ihe mere eme nke ihe karịrị 100 afọ. iji gwọọ onye na-arịa ọrịa cancer ovarian, ụkọ ogologo oge nke ọkọnọ na ọnụ ahịa dị elu na-eme ka nkà na ụzụ mmepụta ihe nke paclitaxel na-eto ngwa ngwa.

Dị ka ihe a na-amịpụta site na osisi eke, paclitaxel nwere usoro dị mgbagwoju anya. Otú ọ dị, iji dozie ụkọ akụrụngwa, ndị na-ahụ maka chemists si gburugburu ụwa na-amụ njikọ nke paclitaxel. Ruo mgbe onye French chemist kewara ihe a na-akpọ.10-DABsite na akwụkwọ nke British Taxus chinensis, usoro ya yiri nke paclitaxel, ọdịnaya ya dị elu. Akwụkwọ ahụ na-emezigharị karịa ogbugbo na alaka, na-enwekwa obere mmebi na Taxus chinensis.

Site unremitting mgbalị nke ndị ọkà mmụta sayensị, usoro nkeSemi-synthetic paclitaxelemechara mebe ya, ọ dịghịkwa mkpa igbutu Taxus chinensis iji wepụ ya. E mesịa, site n'ịmụ usoro nke paclitaxel, e mepụtara ọgwụ ndị ọzọ dị ka docetaxel na albumin paclitaxel, na-ebute ọgwụ ndị ọzọ na-agwọ ọrịa na ndị ọrịa cancer.

Nkọwa: Enwere ike ịrụ ọrụ na ngwa ndị a kpọtụrụ aha n'isiokwu a niile sitere na akwụkwọ ọha nwere.

Ọgụgụ agbatịkwuru:Hande Bio-tech na-etinyekarị aka na mmịpụta na mmepe nke taxisi, ngwaahịa ya bụ paclitaxel eke, 10-DAB Semi-synthetic paclitaxel, 10-DABIII, docetaxel, cabataxel, wdg. Ọ bụrụ na ịchọrọ ịma gbasara paclitaxel. API dabere, biko nweere onwe gị ịkpọtụrụ anyị.